All About Alkylamides


With the ever-growing understanding of CBD and the endocannabinoid system, new and surprising discoveries often come to light. For example, research has shown that phytocannabinoids from Cannabis sativa are not the only plant-derived compounds that can directly interact with our endocannabinoid system (ECS). Alkylamides, a group of lipidic compounds found in a variety of botanicals including Echinacea purpurea, can also have a wide array of effects on the ECS. 


Alkylamides are structurally similar to anandamide, one of the endocannabinoids essential to the function of the endocannabinoid system. This classifies them as a cannabinomimetic, meaning they may function similarly to cannabinoids. However, alkylamides do seem to have distinguishing effects apart from their phytocannabinoid cousins. Namely, these compounds  support healthy cellular activity of the immune system.†


One of the many elements of the endocannabinoid system responsible for supporting our immune systems are the CB2 receptors, located primarily in immune cells throughout the body. Due to the structural similarity between alkylamides and anadaminde, alkylamides have a selective affinity for CB2 receptors. It’s possible that this interaction is largely responsible for the incredible effects of Echinacea purpurea on our immune systems.


These versatile compounds are not only allies to our immune systems, but also to our palates! Alkylamides can have a distinct, spicy taste, sometimes even causing a tingling sensation in the mouth. Alkylamides are also responsible for the mouth-numbing effect that comes from eating Spilanthes, also known as the “toothache berry.” Thankfully, our Dynamic Immune CBD Soft Gels are encapsulated in bovine gelatin, completely bypassing the odd taste that may come with echinacea or alkylamides. 

Whether you are looking to support your immune system or have a sensational party in your mouth, alkylamides can do the trick! Since different plants contain various amounts of alkylamides, our Growth and Innovation Team, led by a Certified Clinical Herbalist, carefully selected an alkylamide-rich ingredient for our Dynamic Immune CBD Soft Gels. These soft gels feature an organic CO2 extract of Echinacea purpurea, which contains 23% alkylamides. If you’re interested in experiencing the brilliant intelligence of plants, consider adding this flower warrior to your supplement regimen!