be_ixf;ym_201912 d_08; ct_50

ECS 101: An Intro Course to the Endocannabinoid System

Bluebird Botanicals Endocannabinoid System

If you’ve engaged in any dialogue about CBD, you’ve probably heard it a million times: everybody’s got an endocannabinoid system. But what exactly does that mean? 

Welcome to Bluebird Botanicals Cannabis Crash Course. This is ECS 101, or Intro to the Endocannabinoid System. 

Let’s begin.

Your endocannabinoid system is one of the largest neurotransmitter networks in the body. It helps promote homeostasis in your body for things like mood, sleep, stress, and appetite, to name a few. All vertebrate mammals have an endocannabinoid system, which essentially just means all mammal bodies are naturally wired to make use of cannabinoids in maintaining homeostasis within various bodily processes.

Let’s Break it Down

Like any major regulatory system in the bodies of humans, the endocannabinoid system is pretty critical.

Conceptualizing the endocannabinoid system breaks down into understanding three key components:

  1. Cannabinoid receptors
  2. Endocannabinoids, or signaling molecules that are naturally present in vertebrates
  3. Phytocannabinoids

Cannabinoid Receptors

We’re talking primarily about CB1 and CB2 here. These receptors are found throughout your brain and body. 

  • CB1 receptors are located within your central nervous system, brain, and spinal cord
  • CB2 receptors are located in the peripheral nervous system, brain, immune system, and gut

There are other types of receptors that play a role in processes of the endocannabinoid system, but these two are the primary players we want to come to know and love in ECS 101.

While it’s a smidge more complicated than this metaphor conveys, receptors are the “lock” in the “lock-and-key” scenario. Signaling molecules like synthetic and phytocannabinoids “fit” into these receptors and “unlock” different bodily processes as a result. 

Endocannabinoids

Endocannabinoids are cannabinoids that are produced within the body. There are two primary endocannabinoids: Anandamide (AEA) and 2-arachidonoylglyerol (2-AG).

  • AEA a partial agonist to CB1 and CB2, and is similar to THC
  • 2-AG is a full agonist to CB1 and CB2

What the heck is an agonist? An agonist is basically a signalling molecule that has a natural affinity for or tends to bind or interact with certain receptors. In the simplest terms, it’s the key that fits the lock.

Phytocannabinoids

Phytocannabinoids are cannabinoids that are found within plants. There are also synthetic cannabinoids or man-made versions that mimic phytocannabinoids. There are three main phytocannabinoids: THC, CBD, and CBD-A.

  • THC is an AEA mimetic, meaning it is a partial CB1 and CB2 agonist and acts similarly to endocannabinoid AEA
  • CBD does NOT bind directly to receptors but rather modulates receptor activity
  • CBD-A or “raw CBD,” which interacts primarily with other enzymes

Want to learn even more about the endocannabinoid system, including the roles of enzymes and terpenes? Stay tuned for the next segment in Bluebird’s Cannabis Crash Course, ECS 102.

Leave a Reply

More Products

Classic
Hemp Classic CBD OilOut of Stock

250+ mg cannabinoids per ounce. Hemp CBD oil extract & organic hemp seed oil.

Details
Complete
Hemp Complete CBD OilOut of Stock

250+ mg raw & heated cannabinoids per ounce, plus hemp terpenes.

Details
Signature
Bluebird Hemp SignatureOut of Stock

250+ mg cannabinoids per ounce. Classic blend plus frankincense & black seed oil.

Details
Sample Pack
Hemp Sample PackOut of Stock

10 ml bottles of Classic, Complete & Signature. 250+ mg total cannabinoids.

$32.95 Details
Classic 6x
Hemp Classic 6x Concentrated CBD OilOut of Stock

1,500+ mg cannabinoids per ounce. Hemp extract & organic hemp seed oil.

Details
Complete 6x
Hemp Oil Concentrate Complete 6xOut of Stock

1,500+ mg raw & heated cannabinoids per ounce, plus hemp terpenes.

Details
Signature 6x
Full-Spectrum Hemp Oil Signature 6xOut of Stock

1,500+ mg cannabinoids per ounce. Classic blend with frankincense & black seed oil.

Details
6x Sample Pack
Concentrated Hemp Oil Sample PackOut of Stock

10 ml bottles of Classic 6x, Complete 6x & Signature 6x. 1,500+ mg cannabinoids.

$129.95 Details
Hemp CBD Silk Lotion
Hemp CBD Silk LotionOut of Stock

Gentle CBD topical cream made with full-spectrum hemp extract, essential oils, jojoba, and coconut…

Details
Hemp CBD Essential Lotion
Hemp CBD Essential LotionOut of Stock

CBD lotion made with full-spectrum hemp extract, jojoba, carrot, and coconut oil. Available in…

Details
Hemp CBD Sport Lotion
Hemp CBD Sport LotionOut of Stock

CBD sports cream made with full-spectrum hemp extract, ginger, arnica, mint, jojoba, and coconut…

Details
Hemp CBD Capsules
Hemp CBD CapsulesOut of Stock

Hemp CBD capsules with full-spectrum hemp extract & organic virgin hemp seed oil. 5…

Concentrated CBD Capsules
Concentrated CBD CapsulesOut of Stock

CBD capsules with full-spectrum hemp extract & organic hemp seed oil. 15 mg of…

Sale!
CBD Vape Juice
CBD Vape JuiceOut of Stock

CBD Vape Juice. 1,000+ mg cannabidiol (CBD) per ounce of vape juice.

Prices shown include discount.
Details
CBD Isolate
CBD Isolate PowderOut of Stock

96%-99.9% pure isolated cannabidiol (CBD). Always 3rd party lab tested.

Details
CBD Isolate Wholesale
CBD Isolate WholesaleOut of Stock

96%-99.9% isolated cannabidiol (CBD). Bulk CBD isolates available at wholesale cost.

Details
Companion Oil
Companion CBD Hemp Oil For Dogs & CatsOut of Stock

250 mg cannabinoids per ounce. CBD hemp oil & organic virgin hemp seed oil.

Details
Companion Capsules
Companion CBD Capsules For PetsOut of Stock

CBD hemp extract & organic virgin hemp seed oil. 5 mg cannabinoids per soft…

Concentrated Companion Capsules
Concentrated Companion CBD CapsulesOut of Stock

CBD hemp extract & hemp seed oil. 15 mg of cannabinoids per soft gel…

THC Free CBD Oil
THC Free CBD OilOut of Stock

1500+ mg CBD per ounce. Hemp CBD isolate & organic fractionated coconut (MCT) oil…

Details